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C 反应蛋白(CRP)是炎症急性期的反应物,正常情况下缺乏,炎症时增高。有关 CRP 在长期血透中的报道不多,且有相反结论。本文采用比浊计免疫分析法对无明显并发症的血透患者、保守治疗的尿毒症患者和健康成人,测定血清 CRP 浓度并作比较,旨在阐明长期血透对 CRP 的复杂影响。病人和方法 99例终末期慢性肾衰患者(血清肌酐>10mg/dl)分为两组。A 组30例,男性17例、女性13例,年龄18～74(平均49.2)岁,给予低蛋白饮食。B 组69例,男性38例、女性31例,年龄19～78(平均57.6)岁,每周血透10～15小时,持续时间1～201(平均66.8)月。肾衰原因均为原发性肾脏病。检测 CRP 前的4周内均无感染、外伤或手术史。
C-reactive protein (CRP) is a reaction of the acute phase of inflammation, lack of normal circumstances, increased inflammation. There are few reports of CRP in long-term hemodialysis, and the opposite conclusion. In this paper, turbidimetric immunoassay for non-complication of hemodialysis patients, conservative treatment of uremic patients and healthy adults, serum CRP concentrations were compared and compared to clarify the long-term hemodialysis CRP complex impact. Patients and Methods Ninety-nine patients with end-stage chronic renal failure (serum creatinine> 10 mg / dl) were divided into two groups. A group of 30 patients, 17 males and 13 females, aged 18 to 74 (mean 49.2) years old, given a low-protein diet. Group B, 69 cases, 38 males and 31 females, aged 19 to 78 (mean 57.6) years of age, hemodialysis for 10 to 15 hours per week for a duration of 1 to 201 (average 66.8) months. Causes of renal failure are primary kidney disease. No infection, trauma or surgery history within 4 weeks before CRP testing.