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作者报道1例80岁农民因皮肌炎入院。患者右臂有一紫色斑块,表面有干痂,该处2年前曾被茅草引起轻度外伤。患者开始用硫唑嘌呤和强的松治疗,斑块发展迅速。活检示真皮内肉芽肿样炎症伴大量巨细胞、浆细胞和淋巴细胞浸润,偶见嗜酸细胞。巨细胞含过碘酸阳性的圆形真菌和分生孢子链。某些部位有较多分隔和分枝菌丝。有小脓肿存在。乌洛托品硝酸银染色证实菌丝和分生孢子。活
The authors report a case of 80-year-old peasants hospitalized for dermatomyositis. The patient had a purple plaque in his right arm and a dry scab on the surface, causing mild traumatic injury to thatch 2 years ago. Patients started treatment with azathioprine and prednisone, plaques developed rapidly. Biopsy showed intradermal granulomatous inflammation with a large number of giant cells, plasma cells and lymphocytes infiltration, and occasionally eosinophils. Giant cells contain periodic acid-positive round fungi and conidia chains. Some parts have more separation and mycelium. A small abscess exists. Urotropine silver nitrate stain confirmed mycelium and conidia. live