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正阳醒脑是根据中医“益肾醒脑、通络化浊”治则研制而成的中药复方胶囊制剂,临床用于治疗心脑血管疾病。经动物实验证实,可明显升高麻醉犬脑血流量,扩张脑血管增加脑组织供血;升高冠脉血流量扩张冠脉血管增加心肌供血,使得脑组织及心肌缺血(缺氧)得以改善。对大鼠实验性血栓形成模型,可延缓血管堵塞时间(OT值),抑制动脉血栓形成。对大鼠实验性脑缺血有明显的保护作用。表明正阳醒脑胶囊对阻塞及缺血性脑血管病有治疗作用。
Zhengyang Xingnao is a traditional Chinese medicine compound capsule preparation developed according to the Chinese medicine “Yishen Xingnao, Tongluo Huazhuo” and is used clinically to treat cardiovascular and cerebrovascular diseases. The animal experiments confirmed that cerebral blood flow in anesthetized dogs can be significantly increased, cerebral blood vessels can be expanded to increase blood supply to the brain, and coronary blood flow can be increased to dilate coronary blood vessels to increase myocardial blood supply, and brain tissue and myocardial ischemia (hypoxia) can be improved. . The experimental thrombosis model in rats can delay vascular occlusion (OT value) and inhibit arterial thrombosis. It has obvious protective effect on experimental cerebral ischemia in rats. It shows that Zhengyang Xingnao Capsule has therapeutic effects on obstruction and ischemic cerebrovascular disease.