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将利用分立器件设计的4通道神经信号再生电子系统成功地应用于大鼠和家兔的活体动物实验,再生了它们的神经信号.采用相同的原理,用CSMC0.6μmCMOS工艺设计实现了单通道神经信号再生集成电路.电路由增益可调的神经信号探测电路、缓冲器和神经功能电激励电路构成.电路采用±2.5V双电源电压供电.芯片尺寸为1.42mm×1.34mm.在片测试电路的静态功耗小于10mW,输出电阻为118mΩ,3dB带宽大于30kHz,增益在50~90dB可调.电路芯片与卡肤电极、针状双体电极一起,用于大鼠的神经信号再生的活体动物实验,成功地再生了大鼠的坐骨神经和脊髓神经信号.
The 4-channel neural signal regenerative electronic system designed with discrete devices was successfully applied to in vivo animal experiments in rats and rabbits to regenerate their neural signals.Using the same principle, the CSMC0.6μm CMOS technology was used to design a single-channel nerve Signal regeneration integrated circuit.The circuit consists of adjustable gain neural signal detection circuit, buffer and neural function electric excitation circuit.The circuit adopts ± 2.5V dual power supply voltage.The chip size is 1.42mm × 1.34mm. The static power consumption is less than 10mW, the output resistance is 118mΩ, the 3dB bandwidth is greater than 30kHz, and the gain is adjustable from 50 ~ 90dB. The circuit chip is used in living animal experiment of nerve signal regeneration in rats together with card-skin electrode and acupuncture double electrode , Succeeded in regenerating the sciatic nerve and spinal nerve signals in rats.