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目的:研究应用脑干听觉诱发电位（BAEP）作为监测小儿全麻深度与觉醒的客观指标。方法:选择非神经外科无听力障碍的择期手术患儿45例,ASAI～Ⅱ级,分别施行异丙酚、芬太尼静脉麻醉及异氟醚吸入全身麻醉,观察各波潜伏期（PL）和波间期（IPL）随时间推移及麻醉剂量变化之间的关系。结果:（1）异丙酚静脉麻醉和异氟醚吸入麻醉与剂量呈良好的正相关,即随着麻醉药的浓度（或剂量）的增高,BAEP各波PL及IPL逐渐延长,反之逐渐缩短。（2）I波的潜伏期特性对于控制麻醉深度极为重要。（3）V波监测麻醉具有最佳的稳定性及相关性。（4）停用麻醉药一段时间或患儿基本清醒时,BAEP各波PL和IPL有的仍高于正常值,这是滞后（延迟）反应。（5）BAEP对芬太尼术中的觉醒监测不太敏感,即相关性较差。结论:BAEP各波的潜伏期及峰间期变化,可判断小儿全身麻醉深度,在一定程度上可作为判断觉醒的参考,但应考虑有延迟反应的可能。
Objective: To study the application of brainstem auditory evoked potential (BAEP) as an objective indicator for monitoring the depth and wakefulness of general anesthesia in children. Methods: Forty-five ASAI-Ⅱ children undergoing elective surgery without hearing impairment were enrolled in this study. All animals were anesthetized with propofol and fentanyl, and anesthetized with isoflurane inhalation. The latency (PL) and wave Interval (IPL) over time and changes in anesthetic dose relationship. Results: (1) Propofol intravenous anesthesia and isoflurane inhalation anesthesia showed a good positive correlation with the dose, that is, with the anesthetic concentration (or dose) increased, BAEP wave PL and IPL gradually extended, otherwise gradually shortened . (2) I wave latency characteristics for the control of anesthesia is extremely important. (3) V wave monitoring anesthesia has the best stability and correlation. (4) When the anesthetic was stopped for a period of time or the children were basically awake, the PLEP wave and IPL in each wave were still higher than normal, which was a lag (delayed) response. (5) BAEP is less sensitive to the awakening of fentanyl during surgery, that is, the correlation is poor. Conclusion: The changes of latency and peak interval of BAEP waves can determine the depth of general anesthesia in children, to a certain extent, can be used as a reference to determine the awakening, but should consider the possibility of delayed response.