新生儿多系统器官损害（ＭＳＯＩ）多因出生时窒息所致，研究证实其与血浆内皮素（ＥＴ）合成、释放增加有关〔１～３〕。但ＭＳＯＩ尚可由其它致病因素引发。我们检测３５例新生儿ＭＳＯＩ的ＥＴ水平，并探讨其在ＭＳＯＩ中的致病机制及与重要脏器功能改变的关系，报告如... Newborn multiple system organ damage (MSOI) mostly due to birth asphyxia, studies have shown that plasma endothelin (ET) synthesis and release increased 〔1-3〕. But MSOI can still be caused by other risk factors. We examined 35 neonates MSOI ET levels, and explore its pathogenic mechanism in MSOI and the relationship with the function of important organs, reports such as ...