香豆素(coumarin)在工业上的合成是首先从苯酚经锐莫-堤曼(Reimer-Tiemann)反应制备水杨醛,再从水杨醛经珀金(Perkim)反应而得到。这个方法经作者重复试验,觉得它费原料多,时间长,且产率低(水杨醛产率不能高于35％,第二步产率可至80％)。因此我们又根据什谬克(Shmuk)的工作(C.A.,34,5070(1940))试验了另一种合成方法。这方法利用苯酚与反丁烯二酸在硫酸中失水,失 In the industrial synthesis of coumarin, salicylaldehyde is first prepared from phenol via Reimer-Tiemann reaction and then from salicylaldehyde via Perkim reaction. This method was repeated by the author, think it costs more raw materials, long time, and low yield (salicylaldehyde production rate can not be higher than 35%, the second step yield up to 80%). So we tested another synthesis based on the work of Shmuk (C.A., 34, 5070 (1940)). This method uses phenol and fumaric acid in sulfuric acid in water loss