随着医学科学的不断发展人们逐渐认识到,吸烟不仅危害人的健康,而且能改变一些药物的代谢—主要由于肝脏酶的诱导作用-能对药物疗效引起不可预测的反应,它可以降低药物疗效或增强药效,例如:吸烟可缩短茶碱的半衰期,增加全身的茶碱清除率,并降低其血清波度,其作用机理可能是 With the continuous development of medical science, people come to realize that smoking not only endangers human health, but also changes the metabolism of some drugs - mainly due to the induction of liver enzymes - that can cause unpredictable reactions to drug efficacy, which can reduce drug efficacy Or enhance the efficacy, for example: smoking can shorten the half-life of theophylline, increase the body’s theophylline clearance, and reduce its serum wave, the mechanism may be