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目的了解不同类型刺激对健康老年及青少年的事件相关电位(ERP)的影响。方法对60名青少年及47名老年健康志愿者做单音、图像及汉字结构识别视觉刺激的ERP研究。结果1、外源性成分的比较:(1)单音:男性及女性的P2PL均是老年组长于青少年组(P<0.05);(2)图像:男性Fz、Cz部位的N1PL和女性P2PL均是老年组短于青少年组(P<0.05);(3)汉字结构:男性P2PL和女性N1、P2PL老年组短于青少年组(P<0.05)。2、内源性成分及RT的比较:(1)单音:男性及女性N2、P3PL及RT均是老年组长于青少年组(P<0.05);(2)图像:男性N2PL及C3、Pz部位的P3PL、RT和女性P3PL及RT,老年组长于青少年组(P<0.05);(3)汉字结构:男性P3PL及RT,老年组长于青少年组(P<0.05),女性Fz部位的N2PL,老年组短于青少年组(P<0.05);P3PL及RT,老年组长于青少年组(P<0.05)。结论ERP的性别差异及年龄差异随刺激的不同而变化。
Objective To understand the effects of different types of stimuli on event-related potentials (ERPs) in healthy elderly and adolescents. Methods Sixty adolescents and 47 elderly healthy volunteers were used to make ERP studies of visual stimulation of mono, image and Chinese character structure recognition. (1) Mono tone: Both male and female P2PLs were older than adolescent group (P <0.05); (2) Image: N1PL and female with male Fz and Cz P2PL was shorter in the elderly group than in the adolescent group (P <0.05). (3) Chinese characters structure: male P2PL and female N1, P2PL elderly group was shorter than adolescent group (P <0.05). (1) Mono: N2 N2, P3PL and RT in male and female were all older group than in adolescent group (P <0.05); (2) Image: Male N2PL and C3, (P <0.05); (3) Chinese character structure: male P3PL and RT, the elderly group leader in the adolescent group (P <0.05), female The N2PL in Fz was shorter in the elderly group than in the adolescent group (P <0.05). P3PL and RT, the older group were longer in the adolescent group (P <0.05). Conclusion The gender difference and age difference of ERP vary with the stimulus.