论文部分内容阅读
目的:探讨血清脂蛋白(a)〔LP(a)〕与脑梗塞发病的关系。方法:采用酶联免疫双抗体夹心法(ELISA)对100例脑梗塞患者进行血清LP(a)含量测定,并设健康、疾病组作对照。结果:脑梗塞组LP(a)含量为332.14mg±327.68mg/L,显著高于健康对照组(126.42mg±152.88mg/L)和疾病对照组(168.77mg±247.89mg/L)。脑梗塞组的LP(a)异常率22.00%,明显高于健康对照组(5.16%)和疾病对照组(7.69%)。脑梗塞的相对危险度是健康对照的5.19倍,疾病对照的3.38倍。结论:血清LP(a)含量升高与脑梗塞发病显著相关,是脑梗塞发病的重要危险因素。
Objective: To investigate the relationship between serum lipoprotein (a) [LP (a)] and the incidence of cerebral infarction. Methods: Serum LP (a) levels were measured in 100 patients with cerebral infarction by enzyme-linked immunosorbent assay (ELISA) and healthy and disease groups were taken as control. Results: The content of LP (a) in cerebral infarction group was 332.14mg ± 327.68mg / L, which was significantly higher than that in healthy control group (126.42mg ± 152.88mg / L) and disease control group (168.77mg ± 247.89mg / L). The abnormal rate of LP (a) in cerebral infarction group was 22.00%, which was significantly higher than that in healthy control group (5.16%) and disease control group (7.69%). The relative risk of cerebral infarction is 5.19 times that of healthy controls and 3.38 times of disease controls. Conclusion: The elevated serum LP (a) level is significantly associated with the incidence of cerebral infarction and is an important risk factor for the development of cerebral infarction.