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目的:探讨针对糖尿病早期肾损伤患者,观察选择CysC+α1—MG+β32 MG联合检测的临床诊断价值。方法:选取我院2012年10月-2014年10月糖尿病患者140例,对糖尿病患者的UAER进行测定,将所有糖尿病患者分为C1组(糖尿病早期肾损伤组100例)与C2组(单纯糖尿病组40例)。同期将健康老年人作为C3组(对照组50例)。对比所有研究对象在CysC、α1—MG以及β2-MG等指标含量方面方面存在的差异。结果:C2组CysC以及α1-MG水平高于C3组研究对象明显(P<0.05);C1组CysC、α1-MG以及β2-MG水平高于C2组患者明显(P<0.05)。结论:针对糖尿病肾损伤患者,临床选择CysC+α1-MG+β2-MG联合检测,表现出显著的临床诊断价值。
OBJECTIVE: To investigate the clinical value of combined detection of CysC + α1-MG + β32 MG in diabetic patients with early renal injury. Methods: A total of 140 diabetic patients from October 2012 to October 2014 in our hospital were enrolled in this study. UAER was measured in all patients with diabetes mellitus. All patients with diabetes were divided into C1 group (100 cases of early diabetic kidney injury group) and C2 group (simple diabetic group Group of 40 cases). The same period the healthy elderly as C3 group (control group 50 cases). All subjects were compared in CysC, α1-MG and β2-MG and other indicators of content differences. Results: The levels of CysC and α1-MG in C2 group were significantly higher than those in C3 group (P <0.05). The levels of CysC, α1-MG and β2-MG in C1 group were significantly higher than those in C2 group (P <0.05). Conclusion: The combination of CysC + α1-MG + β2-MG in diabetic patients with renal injury shows significant clinical value.