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目的分析子痫、子痫前期合并非典型部位可逆性后部白质脑病(Reversible Posterior Encephalopathy Syndrome,RPES)的影像学特征及相关因素。方法回顾性分析2010年1月~2015年12月盛京医院确诊的76例子痫、子痫前期合并可逆性后部白质脑病患者的临床与影像学资料,根据颅脑MRI受累部位不同分为典型病例组与非典型病例组,通过对患者的临床表现、生化指标及影像学特点总结,统计分析非典型部位受累的相关因素。结果 44例患者出现非典型部位受累,发生率57.9%,其中双侧基底节受累最为常见(39例,88.6%),其次为小脑受累(14例,31.8%),对非典型部位受累的相关因素进行Logistic回归分析显示,头痛(OR=6.37,CI 1.30~31.33,P=0.023)及痫性发作(OR=5.42,CI 1.68~17.47,P=0.005)与子痫、子痫前期合并非典型部位RPES有关。结论痫性发作、头痛与RPES非典型部位受累有关。
Objective To analyze the imaging features and related factors of reversible posterior encephalopathy syndrome (RPES) of atypical eclampsia and preeclampsia. Methods The clinical and imaging data of 76 patients with eclampsia and preeclampsia with posterior cruciate leucoencephalopathy confirmed by Shengjing Hospital from January 2010 to December 2015 were retrospectively analyzed. According to the locations of MRI involvement in the brain, Case group and atypical case group, through the clinical manifestations of patients, biochemical indicators and imaging features summary, statistical analysis of atypical parts involvement related factors. Results A total of 44 patients had atypical site involvement (57.9%). Bilateral basal ganglia involvement was the most common (39 cases, 88.6%), followed by cerebellar involvement (14 cases, 31.8%), which was associated with atypical site involvement Logistic regression analysis showed that headache (OR = 6.37, CI 1.30-31.33, P = 0.023) and seizure (OR = 5.42, CI 1.68-17.47, P = 0.005) were associated with eclampsia and preeclampsia with atypical Site RPES related. Conclusion Epileptic seizures and headache are related to the involvement of atypical parts of RPES.