常规β-受体兴奋剂喷雾疗法对一些中到重度的哮喘病人疗效不佳。有报道改用硫酸镁治疗这类低反应病者可获成功。本文用随机抽样、双盲和对照研究评价硫酸镁急诊治疗中到重度哮喘的疗效。病人和方法患者38例,年龄18～70岁,患急性哮喘发作就诊,用手持流速计测定最大呼气流速(PEFR)3次, Conventional β-receptor agonist spray therapy is not effective in some moderate to severe asthma patients. It has been reported to magnesium sulfate treatment of such patients with low response can be successful. This randomized, double-blind, and controlled study evaluated the efficacy of magnesium sulfate in the treatment of moderate to severe asthma. Patients and Methods 38 patients, aged 18 to 70 years, suffering from acute asthma attack, measured by hand-held flow meter maximum expiratory flow rate (PEFR) 3 times,