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目的:观察间歇经口至食管管饲(IOE)法对延髓背外侧综合征所致吞咽障碍病人的临床疗效,为该类病人寻找新的治疗方法。方法:将符合入选标准的延髓背外侧综合征病人60例,按入院顺序随机分入IOE组和鼻胃管(NGT)组,每组各30例。两组病人均在控制基础疾病、干预可控危险因素和脑卒中预防用药的治疗基础上给予吞咽功能训练。在治疗期间,两组病人分别采用IOE法和NGT法给予肠内营养(EN)支持。同时,对两组病人入院24 h内和治疗6周后的营养指标和吞咽功能改善情况进行差异性分析。结果:IOE组病人在治疗6周后营养指标和吞咽功能与NGT组比差异均有显著性统计学意义(P<0.05)。结论:IOE法较NGT法更有利于促进延髓背外侧综合征病人的吞咽功能改善。
Objective: To observe the clinical effect of intermittent oral and esophageal feeding (IOE) on patients with swallowing disorder caused by medullary dorsolateral syndrome and to find new treatment methods for such patients. Methods: Sixty patients with medullary dorsolateral syndrome who meet the inclusion criteria were randomized into IOE group and NGT group according to the order of hospital admission, with 30 cases in each group. Both groups were given swallowing training on the basis of control of underlying diseases, intervention of controllable risk factors and prevention of stroke. During treatment, enteral nutrition (EN) support was given to both groups using the IOE and NGT methods, respectively. At the same time, the two groups of patients within 24 h after treatment and 6 weeks after treatment of nutritional indicators and swallowing functional improvement were analyzed. Results: In the IOE group, the difference of the nutritional index and swallowing function between the 6th week and the NGT group was statistically significant (P <0.05). Conclusion: The IOE method is better than the NGT method in promoting the improvement of swallowing function in patients with medullary dorsolateral syndrome.