脑胶质瘤是神经外科最常见的肿瘤之一 ,其较高的复发率使得患者常常需要多次手术 ,成为临床治疗的难题。随着分子生物学及免疫学研究的不断发展 ,基因治疗成为一个突破方向和研究热点。有关基因如何突变、抗癌基因如何杀伤肿瘤细胞及肿瘤细胞抗损伤机制 ,目前国内外学者进行了 Glioma is one of the most common tumors in neurosurgery. The high recurrence rate makes patients often need multiple surgeries and become a difficult problem in clinical treatment. With the continuous development of molecular biology and immunology, gene therapy has become a breakthrough direction and research hotspot. How the mutation of genes, anti-oncogene how to kill tumor cells and tumor cell anti-injury mechanism, at home and abroad scholars