异烟肼与维生素B_6 此问题已争论了20多年,争论可以概括为:(1)是否需常规合用?(2)什么情况下才需要合用?(3)合用后是否影响其抗菌效能? 一、一般剂量下是否需要合用维生素B_6? 一般剂量是指一日3次每次服0.1g异烟肼的常规疗法,在这种用量下,异烟肼的血液浓度较低。据研究,异烟肼的代谢方式,按遗传 Isoniazid and Vitamin B_6 This issue has been debated for over 20 years. The controversy can be summarized as: (1) Is it routinely required to use it? (2) When is it necessary to use it in combination? (3) Does it affect its antimicrobial efficacy after use? Is it necessary to have vitamin B 6 at the usual dose? A typical dose is the usual regimen of 0.1 g of isoniazid at a dose of 3 times a day at a lower blood concentration of isoniazid. According to research, isoniazid metabolism, according to genetic