Lymphangioma of the pancreas is an extremely rare benign tumour of lymphatic origin,with fewer than 60 published cases. Histologically,it is polycystic,with the cysts separated by thin septa and lined with endothelial cells. Though congenital,it can affect all age groups,and occurs more frequently in females. Patients usually present with epigastric pain and an associated palpable mass. Complete excision is curative,even though,depending on the tumour location,surgery may be simple or involve extensive pancreatic resection and anastomoses. The authors present a 49-year-old woman in whom a polycystic septated mass,35 mm x 35 mm in size,was discovered by ultrasonography (US) in the body of the pancreas during investigations for epigastric pain and nausea. At surgery,a well circumscribed polycystic tumor was completely excised,with preservation of the pancreatic duct. The postoperative recovery was uneventful. Histology confirmed a microcystic lymphangioma of the pancreas. Immunohistochemistry showed cystic endothelial cells reactivity to factor Ⅷ -RA (++),CD31 (+++) and CD34 (-). Postoperatively,abdominal pain disappeared and the patient remained symptomfree for 12 mo until now. Although extremely rare,lymphangioma of the pancreas should be taken into consideration as a differential diagnosis of a pancreatic cystic lesion,especially in women. Lymphangioma of the pancreas is an extremely rare benign tumor of lymphatic origin, with fewer than 60 published cases. Histologically, it is polycystic, with the cysts separated by thin septa and lined with endothelial cells. Though congenital, it can affect all age groups, and occurs more frequently in females. Patients usually present with epigastric pain and an associated palpable mass. Complete excision is curative, even though, depending on the location location, surgery may be simple or involve extensive pancreatic resection and anastomoses. -year-old woman in whom a polycystic septated mass, 35 mm x 35 mm in size, was discovered by ultrasonography (US) in the body of the pancreas during investigations for epigastric pain and nausea. At surgery, a well circumscribed polycystic tumor was completely excised, with preservation of the pancreatic duct. The postoperative recovery was uneventful. Histology confirmed a microcystic lymphangioma of the pancreas. Immunohistochem Postoperatively, abdominal pain disappeared and the patient remained symptom free for 12 mo until now. Although extremely rare, lymphangioma of the pancreas should be taken into consideration as a differential diagnosis of a pancreatic cystic lesion, especially in women.