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运用免疫组化和流式细胞计技术，检测45例膀胱癌病理蜡块的P53声达状况及细胞周期、DNA含量等指标。结果显示：P53总阳性率为48．9％（22／45），在浸润型、低分化膀胱癌及非整倍体、高S期细胞百分比（SP）、高细胞增殖指数（PI）肿瘤中有较高表达，并有统计学意义。提示P53过度表达是腿肌癌一种可供选择的客观预后指标。
Immunohistochemistry and flow cytometry were used to detect the expression of P53 and the cell cycle and DNA content in 45 cases of bladder cancer. The results showed that the positive rate of P53 was 48.9% (22/45) in invasive, poorly differentiated bladder cancer and aneuploidy, the percentage of high S phase cells (SP) and high cell proliferation index (PI) tumors Have a higher expression, and have statistical significance. Tip P53 overexpression is an alternative objective prognostic indicator of leg muscle.