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血泌乳素(PRL)升高与多种生殖障碍有关,如闭经,月经过少,无排卵、黄体缺陷性不孕等。但对于原因不明不孕妇女PRL分泌类型却知之甚少。目前已知在不同的病理生理情况下,不同分子量的PRL以不同比例存在于血液中。本研究采用免疫放射(IRMA)检测免疫活性PRL,铌(Niobium Nb_2)淋巴瘤细胞法(Nb_2BA)检测生物活性PRL,旨在比较正常生育和不明原因不孕妇女生物活性及免疫活性血PRL水平的动态变化。 收集符合不明原因不孕诊断的妇女12例为研究组,正常生育妇女12例为对照组。以LH峰日为0d将月经周期划分为:早卵泡期(-10～-6d)、晚卵泡期(-5～-1d)、
Blood prolactin (PRL) increased with a variety of reproductive disorders, such as amenorrhea, menorrhagia, anovulation, corpus luteum infertility and so on. However, for unknown reasons, infertility women PRL secretion type is poorly understood. It is currently known that PRLs of different molecular weights are present in different proportions in the blood under different pathophysiological conditions. In this study, immuno-radiation (IRMA) detection of immune activity of PRL, niobium (Niobium Nb 2) lymphoma cell method (Nb 2 BA) detection of bioactive PRL aims to compare the normal and unexplained infertility women with infertility and immunocompromised blood PRL levels Dynamic changes. Twelve cases of women diagnosed with unexplained infertility were collected as study group and 12 cases of normal fertility women as control group. The day of LH peak is 0d, the menstrual cycle is divided into: early follicular phase (-10 ~ -6d), late follicular phase (-5 ~ -1d)