针孔伽玛相机是研制高分辨率针孔SPECT系统的基础.采用信息论中的信道模型对针孔伽玛相机进行研究.通过面源模型,将针孔伽玛相机从有噪、有损信道近似为一个无噪、无损信道,然后给出了针孔伽玛相机的平均互信息量近似计算公式.成像实验验证了理论公式的适用性.因此,针孔伽玛相机可以用信道模型来描述,平均互信息量可以作为一个性能指数用于针孔伽玛相机的优化设计与使用. Pinhole Gamma camera is the basis for the development of high resolution pinhole SPECT system.The pinhole Gamma camera is studied by channel model in information theory.The pinhole Gamma camera is made from noisy and lossy channel Which is approximately a noiseless and lossless channel, and then gives the approximate calculation formula of average mutual information amount of pinhole gamma camera.The imaging experiment verifies the applicability of the theoretical formula.Therefore, pinhole gamma camera can be described by channel model , The average amount of mutual information can be used as a performance index for the optimal design and use of pinhole gamma cameras.