抗个体独特型抗体疫苗这个名称,乍听起来觉得新鲜且令人费解。因为经典的免疫学关于疫苗的定义是:将微生物接种于动物或组织培养,生长后的收获物经处理或提取微生物的某些组分而制备的具有抗原性的制品。那么,一向作为被动免疫制剂的抗体怎么一跃成为主动免疫用的疫苗呢?这正是本文试图阐明的问题。抗个体独特型抗体疫苗与基因工程疫苗和合成肽疫苗并列,成为现代分子疫苗发展的三大方向。 Anti-idiosyncratic antibodies Vaccine name, at first glance sounds fresh and puzzling. Because classical immunology is defined as a vaccine with an antigenic preparation prepared by inoculating the microorganism in an animal or tissue culture, growing the harvested material, or treating or extracting certain components of the microorganism. So how has the antibody that has been used as a passive immune agent jump into a vaccine for active immunization? That is exactly what the paper tries to elucidate. Anti-idiosyncratic antibody vaccine and genetic engineering vaccine and synthetic peptide vaccine side by side, has become the development of modern molecular vaccine in three directions.