用海水灌注的方法诱导海水淹溺肺水肿（ＰＥ－ＳＷＤ）， 采用高频喷射通气（ＨＦＪＶ） 治疗， 应用血气酸碱分析仪对兔动脉血气酸碱三项指标进行自动检测， 并采用Ｃａ２＋ 超微结构方法观察肺内Ｃａ２＋ 变化。结果表明肺细胞内Ｃａ２＋ 超负荷与ＰＥ－ＳＷＤ发生有关， ＨＦＪＶ 对改善ＰＥ－ＳＷＤ症状有明显作用， 同时， 细胞内Ｃａ２＋ 超负荷状况明显缓解 The sea-water perfusion method was used to induce PE-SWD. HFJV was used to detect the arterial acidity and alkalinity of the rabbits. Micro-structure method to observe changes of Ca2 + in lung. The results showed that intracellular Ca2 + overload was associated with the occurrence of PE-SWD. HFJV had a significant effect on improving the symptoms of PE-SWD. Meanwhile, the intracellular Ca2 + overload was significantly relieved