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颏舌肌的活动状态对上呼吸道开放有重要作用。动物及人体研究表明,颏舌肌活动降低可导致上呼吸道狭窄或阻塞,电刺激颏舌肌可使麻醉狗上呼吸道阻力明显降低。本文主要研究经皮颏舌肌电刺激对阻塞性睡眠呼吸暂停综合征(OSAS)患者上呼吸道开放状态的影响及其用于 OSAS 治疗的可能性。病人和方法选择6例经多导睡眠生理记录仪确诊的 OSAS 患者,用2个心电图电极(直径10 mm)分置于双侧颏下,作为刺激电极。在呼吸停止达5sec后,由呼吸停止依赖型刺激器(apnea demand-typestimulator)发放脉冲电刺激,脉冲间隔0.5 ms,频率50 Hz,电压15～40V,刺激持续1～2sec,自主
The activity of the genioglossus plays an important role in the upper respiratory tract opening. Animal and human studies have shown that a reduction in activity of the genioglossus can result in stenosis or obstruction of the upper respiratory tract and that electrical stimulation of the genioglossus muscle can significantly reduce upper respiratory resistance in anesthetized dogs. This article focuses on the percutaneous genioglossal electrostimulation on obstructive sleep apnea syndrome (OSAS) patients with upper respiratory tract open state and its potential for OSAS treatment. Patients and Methods Six OSAS patients diagnosed by polysomnography were divided into bilateral submental chickens with two electrocardiogram electrodes (10 mm in diameter) as stimulation electrodes. Pulsed electrical stimulation was delivered by an apnea demand-type stimulator at a pulse interval of 0.5 ms, a frequency of 50 Hz and a voltage of 15-40 V for 1 to 2 seconds after respiration was stopped for 5 seconds