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目的通过回顾性分析血液病患者出血时PC与相关因素,计算PC处于各暴露等级时的出血风险。方法回顾性分析2013年7月-2017年6月于南京大学医学院附属鼓楼医院、南京市第一医院、南京市江宁医院血液科住院患者,计算不同血液病的出血风险度。结果 5类血液病对低PC的耐受性相比:AA与ITP能耐受较低的PC水平;MDS与AML(M3除外)较易出血;ALL最易出血。讨论当血小板资源紧缺时,应优先考虑给ALL、MDS与AML患者输注,保证危重患者的生命安全;对于AA与ITP患者,可适当降低血小板输注阈值,减少血小板输注无效的发生率。
Objective To analyze the PC and related factors in hemorrhagic patients with hemorrhagic disease and calculate the risk of bleeding when PC is at each level of exposure. Methods A retrospective analysis of July 2013 - June 2017 at the Drum Tower Hospital Affiliated to Nanjing University Medical College, Nanjing First Hospital, Nanjing Jiangning Hospital hematology inpatients to calculate the risk of hemorrhage of different blood diseases. Results Five types of hematologic diseases were more tolerant to low PC: AA and ITP were able to tolerate lower PC levels; MDS and AML were more likely to bleed; ALL was the most vulnerable to bleeding. Discussion When the shortage of platelet resources, priority should be given to patients with ALL, MDS and AML infusion, to ensure the safety of critically ill patients; for AA and ITP patients, may be appropriate to reduce platelet transfusion threshold, reduce the incidence of platelet transfusion ineffective.