论文部分内容阅读
低剂量全身照射及合并肿瘤组织局部大剂量照射表明 ,低剂量辐射可以诱导肝脏抗氧化酶升高 ;预先给予 0 0 5Gy全身照射 ,6小时后在施以大剂量X射线肿瘤局部照射较单纯施用大剂量照射者肝细胞过氧化脂质 (LPO)含量降低 ,谷胱甘肽过氧化物酶 (GSH -Px)、超氧化物歧化酶 (SOD)活性增强。肿瘤组织病理研究表明 ,应用低剂量辐射 ,肿瘤组织内见明显的毛细血管增生 ,浸润淋巴细胞 (TIL)数增加。研究表明 ,大剂量肿瘤组织照射前采用低剂量全身照射对机体正常组织有保护作用 ,同时也有利于对肿瘤组织的杀伤作用。
Low-dose whole-body irradiation and local high-dose irradiation of tumor tissue showed that low-dose radiation could induce hepatic antioxidant enzymes to increase; pre-administration of total body irradiation with 0 0 5Gy, 6-hour administration of large-dose X-ray tumors with local irradiation was more simple than administration. In large doses, the content of LPO in liver cells decreased, and the activities of glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) increased. Tumor histopathology studies showed that with low-dose radiation, there was a clear capillary hyperplasia in the tumor tissue, and the number of infiltrating lymphocytes (TIL) increased. Studies have shown that low-dose systemic irradiation before irradiation of large doses of tumor tissue has protective effects on normal tissues of the body, and it is also beneficial for the killing effect on tumor tissues.