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目的掌握甘肃省裕固族地区人群的血脂水平及其相关危险因素,为该地区血脂异常防治工作提供科学依据。方法采用随机整群分层抽样方法 ,对裕固族自治县1119名居民进行现况调查、医学体检,检测血浆总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C),分析该地区人群血脂水平分布特征及相关危险因素的聚集性。结果该地区人群TC、TG、LDC-C、HDL-C水平分别为(4.37±1.01),(1.92±1.28),(2.65±0.89),(1.47±0.39)mmol/L,TC、TG水平男性高于女性,HDL-C水平男性低于女性(P<0.01);TC、LDC-C、HDL-C水平裕固族高于汉族和藏族(P<0.01),TG水平汉族高于裕固族和藏族(P<0.05)。TC、TG、LDC-C水平随年龄增长呈上升趋势,各组间差异有统计学意义(P<0.01),65岁组有所下降;高血压、超重、腹型肥胖与血脂水平呈显著相关性(P<0.01)。结论甘肃省裕固族地区居民血脂水平高于全国,血脂水平与超重肥胖、腹型肥胖、高血压具有显著相关性。
Objective To understand the level of blood lipids in the Yugu people in Gansu Province and its related risk factors so as to provide a scientific basis for the prevention and treatment of dyslipidemia in this area. Methods A total of 1119 inhabitants of Yugur Autonomous County were investigated by random cluster stratified sampling method. Physical examination, plasma total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C) , High-density lipoprotein cholesterol (HDL-C) were measured. The distribution characteristics of blood lipids in this population and the aggregation of related risk factors were analyzed. Results The levels of TC, TG, LDC-C and HDL-C in the population were 4.37 ± 1.01, 1.92 ± 1.28, 2.65 ± 0.89, 1.47 ± 0.39 mmol / L, The levels of TC, LDC-C and HDL-C in Yugu people were higher than those in Han and Tibetans (P <0.01), and those in TG level were higher than those in Yugu and Tibetans (P <0.05). The levels of TC, TG and LDC-C showed an upward trend with age, with significant difference between the groups (P <0.01), but decreased at the age of 65. Hypertension, overweight and abdominal obesity were significantly correlated with blood lipid levels (P <0.01). Conclusion The level of blood lipid in Yugu people in Gansu Province is higher than that in China. The level of blood fat is significantly correlated with overweight and obesity, abdominal obesity and hypertension.