百日咳脑病是百日咳的严重并发症,其抽搐频繁,易发生呼吸衰竭,死亡率高,我们曾治疗百日咳脑病44例,病死率为34.9%(15例/44例),因此,为降低百日咳脑病的病亡率,进一步探讨百日咳脑病的有效治疗方法是很必要的。自1976年起,我们应用抗胆碱药治疗重症百日咳脑病31例,病死率为16.1%(5例/31 Pertussis encephalitis is a serious complication of pertussis. It has frequent convulsions, respiratory failure and high mortality. We have treated 44 cases of whooping cough encephalopathy with a mortality rate of 34.9% (15 cases / 44 cases). Therefore, in order to reduce the incidence of pertussis The mortality rate, to further explore the effective treatment of whooping cough encephalopathy is necessary. Since 1976, we applied anticholinergic drugs to treat 31 cases of severe whooping cough encephalopathy with a mortality rate of 16.1% (5 cases / 31