神经降压肽(neurotensin NT)为一13肽,用免疫组织化学及放射免疫学等方法证明;NT在中枢神经系统内主要分布于脊髓背角及三叉神经脊囊核的胶质伏隔核,下丘脑、视前区、脚间核、中脑中央灰质、杏仁核、缰核,嗅皮质等处。注射NT于中枢神经内,有加强巴比妥的镇痛、催眠及降低小鼠直肠温度等效应。其降低体温的效应可因用右旋氨基酸代替C-端的一般左旋氨基酸而消失。若先 Neurotensin NT was a 13-peptide, which was proved by immunohistochemistry and radioimmunology. NT was mainly located in dorsal horn of spinal cord and trigeminal nerve nucleus of glial nucleus accumbens in the central nervous system, Hypothalamus, preoptic area, intermediate nucleus, central gray matter in the brain, amygdala, habenular nucleus, and olfactory cortex. NT injection in the central nervous system, there is to strengthen the barbiturates analgesia, hypnosis and reduce the rectal temperature effects in mice. Its effect of lowering body temperature disappears by replacing the C-terminal normal L-amino acids with D-amino acids. If first