论文部分内容阅读
支气管扩张剂舒喘灵(salbutamol,选择性β_2肾上腺受体制剂)和茶硷(一种甲基嘌呤)常用于治疗气道阻塞。茶硷的治疗指数低,过量可能危险。本文报告40例口服过量舒喘灵的症状和后果。1979～1980年确诊为服用舒喘灵过量患者40例入院治疗,其中20例曾洗胃或用吐根糖浆催吐。2例血清钾测定分别为2.2和2.6mEg/L,患者均无发生室性心律失常,血液动力学保持稳定。10例给过β肾上腺素能受体阻滞剂。心得安是最常用的药物,4例<10岁患儿口服剂量为5～10mg;6例>10岁口服10～80mg。仅1例静脉使用β阻滞剂(心得宁10mg),所有患者都安全恢复。
Bronchodilators salbutamol (selective β_2 adrenergic receptor preparation) and theophylline (a methylpurine) commonly used in the treatment of airway obstruction. Theophylline treatment index is low, excessive may be dangerous. This article reports the symptoms and consequences of orally administered salbutamol in 40 patients. From 1979 to 1980, 40 patients who were diagnosed with excessive doses of salbutamol were admitted to the hospital for treatment, of whom 20 had gastric lavage or euthanized with ipecac syrup. Two cases of serum potassium were 2.2 and 2.6 mEg / L, no patients had ventricular arrhythmia, hemodynamic stability. Ten patients had given beta adrenergic receptor blockers. Adrenaline is the most commonly used drugs, 4 cases of <10 years old children oral dose of 5 ~ 10mg; 6 patients> 10 years old oral 10 ~ 80mg. Only 1 patient received intravenous β-blocker (10 mg of naringin) and all patients recovered safely.