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目的探讨抗肿瘤中药药效学研究与评价的关注点。方法通过近年来对抗肿瘤中药药效学评价的认识和思考,总结此类药物药效学研究中存在的问题,对如何进行药效学研究和评价进行探讨。结果与结论抗肿瘤中药的研发应以临床意义为方向合理立题,根据拟临床定位并结合中药特点进行药效学试验设计和研究,药效学研究和评价应有机结合。
Objective To investigate the points of concern on the pharmacodynamics research and evaluation of anti-tumor traditional Chinese medicine. Methods Based on the cognition and thinking of pharmacodynamics evaluation of anti-tumor traditional Chinese medicine in recent years, the problems existing in pharmacodynamics research of these drugs were summarized, and the research on pharmacodynamics and evaluation were discussed. RESULTS AND CONCLUSIONS The development of anti-tumor traditional Chinese medicine should be based on the clinical significance of a reasonable direction, according to the clinical positioning and the characteristics of traditional Chinese medicine pharmacodynamic test design and research, pharmacodynamics and evaluation should be combined.