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目的总结分析新生儿贫血输注红细胞的效果,为更好地指导新生儿输血治疗提供参考依据。方法搜集2007年1月~2009年12月住院的贫血新生儿输注悬浮红细胞前后的数据,包括悬浮红细胞的输入量、血液常规、生化、血气等检查,进行回顾性分析。结果 1)1 387名贫血新生儿中,有916例接受悬浮红细胞输注治疗,占贫血新生儿的66.04%;2)输注悬浮红细胞后Hb、RBC、Hct和WBC均显著性升高。Hb平均提升35.56 g/L,RBC计数平均提升1.3×1012/L,Hct平均提升9%,但对血气、血液生化等监测值无显著影响;3)输注悬浮红细胞的贫血新生儿,有7.42%的患儿Hb≤80 g/L,23.14%患儿的Hb为(80~100)g/L,30.19%患儿的Hb为(100~1300)g/L,38.65%患儿的Hb为(130~145)g/L。结论输注悬浮红细胞能显著提高贫血新生儿的Hb、Hct和红细胞计数水平,改善患儿供氧状况。输血指征的把握尚需探讨。
Objective To summarize and analyze the effect of erythrocytes transfusion in neonatal anemia, so as to provide a reference for better guiding neonatal transfusion therapy. Methods Data were collected before and after transfusion of erythrocytes from January 2007 to December 2009 in neonates with anemia, including the input of suspended erythrocytes, blood routine, biochemical and blood gas examination. The data were retrospectively analyzed. Results 1) Of the 1 387 newborn infants with anemia, 916 received transfusion of RBC, accounting for 66.04% of newborns with anemia; 2) Hb, RBC, Hct and WBC increased significantly after transfusion of erythrocytes. Hb increased by 35.56 g / L on average, RBC count increased by 1.3 × 1012 / L on average and Hct increased by 9% on average, but had no significant effect on blood gas and blood biochemistry. 3) Infants with suspended erythrocytes had 7.42 % Of children with Hb ≤ 80 g / L, 23.14% of children with Hb (80 ~ 100) g / L, 30.19% of children with Hb (100 ~ 1300) g / L, 38.65% of children with Hb (130 ~ 145) g / L. Conclusion Infusion of erythrocytes can significantly improve the level of Hb, Hct and erythrocyte count in neonates with anemia and improve oxygen supply in children. Blood transfusion indications need to be explored.