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Ｐ５３基因异常与肿瘤发生密切相关。将外源性野生型Ｐ５３导入妇科恶性肿瘤细胞，在体外及动物实验中均出现了抑制肿瘤细胞生长及使肿瘤细胞出现凋亡的现象，故认为Ｐ５３基因治疗妇科肿瘤很有前途。
P53 gene abnormalities are closely related to tumorigenesis. The introduction of exogenous wild-type P53 into gynecological malignant tumor cells in vitro and in animal experiments have emerged to inhibit tumor cell growth and tumor cell apoptosis, so that P53 gene therapy gynecologic oncology is promising.