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Survivin是IAP家族的新成员,具有抑制细胞凋亡和调节细胞有丝分裂两个方面的作用。Survivin广泛表达于人类常见恶性肿瘤组织,而在正常成人组织和终末分化的组织内检测不到,因而为肿瘤的诊断和靶向治疗提供了一个良好的前景。
Survivin is a new member of the IAP family, with the role of inhibiting apoptosis and regulating cell mitosis. Survivin is widely expressed in human common malignant tumor tissues and undetectable in normal adult tissues and terminally differentiated tissues, thus providing a good prospect for tumor diagnosis and targeted therapy.