Aladan scanning: The structure-activity relationship of dynorphin A

来源 :中国科学：化学英文版 | 被引量 : 0次 | 上传用户：nemosan

【摘要】

：

An unnatural amino acid, β-[6′-(N, N-dimethyl)amino-2′-naphthoyl]alanine (Ald) showing polarity-sen sitive fluorescence characteristics, was synthesized. A t

【作者】

：

HeRu Chen (1) (2) Yang Yang

【机构】

：

1.InstituteofTraditionalChineseMedicineandNaturalProducts,2.DepartmentofChemistry

【出处】

：

中国科学：化学英文版

【发表日期】

：

2009年3期

【关键词】

：

aladan DYNORPHIN A FLUORESCENT AMINO ACID FLUORESCENT PEPTIDE aladan dynorphin A

【基金项目】

：

Supported by the National Natural Science Foundation of China (Grant No. 30672560),the Ascended Project for Natural Scientific Research of Universities in Guangdong Province (Grant No. 05Z012)

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An unnatural amino acid, β-[6′-(N, N-dimethyl)amino-2′-naphthoyl]alanine (Ald) showing polarity-sen sitive fluorescence characteristics, was synthesized. A thorough Ald-scan of dynorphin A (Dyn A), the putative endogenous ligand for κ opioid receptors, wa

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Aladan scanning: The structure-activity relationship of dynorphin A

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