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本文报告江门市区疾病监测点实施0～6岁人群乙肝疫苗系统免疫方案四年半(1986.1～1990.6)的血清学和流行病学监测结果。发现实施系统免疫后0～6岁人群HBsAg阳性率逐年下降,由免疫前的8.36％下降至2.15％,抗-HBs水平逐年上升,由18.81％上升到82.79％,0～6岁乙肝特异发病率下降95.75％。提示在乙肝高发区实施乙肝疫苗计划免疫能在较短时间内控制乙肝发病率和感染率。但注苗者免后三年抗体水平已有明显下降。作者提出新生儿完成基础免疫后在3～4周岁进入幼儿园时应及时给予加强免疫。
This article reports the serological and epidemiological surveillance results of the hepatitis B vaccine system immunization program for people aged 0 ~ 6 years (1986.1 ~ 1990.6) in Jiangmen downtown area. The results showed that the positive rate of HBsAg in the population aged 0-6 was decreased from 8.36% before immunization to 2.15%, the level of anti-HBs increased year by year from 18.81% to 82.79%, and the specific incidence of hepatitis B Down 95.75%. Prompted in the high incidence of hepatitis B hepatitis B vaccine immunization program in a relatively short period of time to control the incidence of hepatitis B and infection rates. However, vaccination vaccine-free three years after the antibody levels have dropped significantly. The authors suggest that newborns should be boosted in time when they enter kindergarten at the age of 3 to 4 after completing basic immunization.