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既往的研究表明奥美拉唑有抑制幽门螺杆菌(HP)的作用。采用含有羟氨苄青霉紊的抗菌疗法能有效地根除 HP,治愈十二指肠溃疡(DU),但有副作用较多的缺点。本文研究奥美拉唑加羟氨苄青霉素是否可以根除 HP,同时减少副作用。病人和方法 DU 病人60例随机分组。病人年龄18～75岁,溃疡直径≥5mm。剔除有胃溃疡或幽门管溃疡、内镜检查前4周内有服铋剂、抗生素、皮质类固醇和非甾体类消炎药者。胃镜检查时于胃窦取活检二块用于 HP 培养,胃窦及胃体各取二块用于组织学及 HP 银染色检查。所有病人于胃镜检查后即接受治疗,如随
Previous studies have shown that omeprazole can inhibit the role of Helicobacter pylori (HP). Antibacterial therapy with amoxicillin can effectively eradicate HP and cure duodenal ulcer (DU), but there are many side effects. This article studies whether omeprazole plus amoxicillin can eradicate HP while reducing side effects. Patients and Methods DU patients were randomly divided into two groups. Patient age 18 to 75 years old, ulcer diameter ≥ 5mm. Excluded gastric ulcer or pyloric ulcer, bismuth, antibiotics, corticosteroids and non-steroidal anti-inflammatory drugs within 4 weeks before endoscopy. Gastroscopy in the stomach to take biopsy two for HP culture, gastric and corpus take two each for histology and HP silver staining. All patients underwent gastroscopy after treatment, such as with