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5. Analytical consideration of the selectivity of oligonucleotide hybridization

Analytical consideration of the selectivity of oligonucleotide hybridization

来源 :生物物理化学(英文) | 被引量 : 0次 | 上传用户：styi613

【摘 要】

：

Systematic analysis of factors determining efficiency in discrimination of a point substitution (SNP) within specific DNA sequences was carried out in the conte

【作 者】

：

M. R. Kabilov D. V. Pyshnyi 

【机 构】

：

InstituteofChemicalBiologyandFundamentalMedicineSBRAS

【出 处】

：

生物物理化学(英文)

【发表日期】

：

2011年2期

【关键词】

：

ALLELE Specific HYBRIDIZATION DUPLEX Stability OLIGONUCLEOTIDE Probes SNP Discri 

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Systematic analysis of factors determining efficiency in discrimination of a point substitution (SNP) within specific DNA sequences was carried out in the context of hybridization approach. There are two types of selectivity that are critical for the rati

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