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应用抗酸(IK)染色和结核菌抗体(BCG)、增殖细胞核抗原(PCNA)免疫组化染色方法,对119例膀胱肿瘤及炎症进行了检测。结果显示:IK抗酸染色、BCG免疫组化染色阳性率分别为:膀胱癌为352、367%;乳头状瘤为40%、44%;慢性炎为423%、50%。PCNA阳性细胞指数膀胱癌与粘膜慢性炎比较差异非常显著(P<0001);乳头状瘤与慢性炎比较差异显著(P<005)。提示结核菌L型感染与肿瘤的发生和发展可能有关
119 cases of bladder tumor and inflammation were detected by anti-acid (IK) staining, anti-tuberculosis antibody (BCG) and proliferating cell nuclear antigen (PCNA) immunohistochemical staining. The results showed that the positive rate of IK acid-fast staining and BCG immunohistochemical staining were 35.2% and 36.7% for bladder cancer, 40% and 44% for papilloma, 42.3% and 50% for chronic inflammation %. PCNA positive cell index bladder cancer and mucosal chronic inflammation was significantly different (P <0 001); papilloma and chronic inflammation were significantly different (P <0 05). Tip L tuberculosis infection and tumor occurrence and development may be related