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目的:评价华蟾素治疗湿热型恶性腹水的临床疗效及不良反应。方法:共纳入湿热型恶性腹水患者60例,其中治疗组45例,对照组15例,分别给予华蟾素50 ml、白介素-2注射液40万单位腹腔灌注,每周2次,2周为1个疗程,1个疗程后进行疗效评价。结果:治疗组完全缓解2例,部分缓解13例,未完全缓解15例,无效15例,有效率为66.7%,对照组为46.7%。结论:华蟾素腹腔灌注治疗湿热型恶性腹水具有一定临床疗效且毒副作用低,值得进一步研究。
Objective: To evaluate the clinical efficacy and adverse reactions of cinobufacini in the treatment of damp-heat malignant ascites. Methods: A total of 60 patients with hydrothermal malignant ascites were enrolled. Among them, 45 patients in the treatment group and 15 patients in the control group were given cinobufagin 50 ml and interleukin-2 injection 400000 peritoneal perfusion twice a week for 2 weeks A course of treatment, a course of treatment for evaluation. Results: In the treatment group, 2 cases were completely relieved, 13 cases partially relieved, 15 cases were not completely relieved, 15 cases were ineffective. The effective rate was 66.7% and 46.7% in the control group. Conclusion: Cinobufacini intraperitoneal perfusion treatment of damp-heat malignant ascites has a certain clinical efficacy and low toxicity, it is worth further study.