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再生性牙髓治疗又称牙髓血管再生治疗,是年轻恒牙感染牙髓治疗的新选择。牙源性干细胞是参与再生性牙髓治疗中组织再生的三大要素之一。根管内炎症因子长期刺激将会导致根管内稳态的破坏,干细胞难以发挥其应有的作用。根管消毒是控制根管内感染、形成有利于干细胞发挥作用的微环境的关键步骤,但根管消毒材料本身对干细胞的作用不容忽视。文章将常用的根管消毒材料对牙源性干细胞的作用研究进展做一综述。
Regenerative pulp therapy, also known as dental pulp regeneration, is the new choice of dental pulp treatment of young permanent tooth infection. Odontogenic stem cells are one of the three major factors involved in tissue regeneration in regenerative endodontic treatment. Long-term stimulation of inflammatory factors in the root canal will lead to the destruction of the root canal homeostasis, stem cells are difficult to play its due role. Root canal disinfection is a key step in controlling the root canal infection and creating a microenvironment conducive to stem cell function, but the role of root canal disinfection materials on stem cells can not be ignored. The article reviews the research progress of the commonly used root canal disinfection materials on the role of odontogenic stem cells.