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目的观察控制性过度通气治疗小儿脑疝的疗效。方法对10例脑疝患儿在常规治疗同时行控制性过度通气治疗,并与23例常规治疗的脑疝患儿作对照。结果对照组死亡21例,抢救成功2例。治疗组除3例放弃治疗而死亡外,全部抢救成功。两组比较差异非常显著(P<001)。两组抢救成功者治疗期间昏迷评分(Glasgow评分法)≥8分的平均时间治疗组为(1614±1036)h,对照组为(335±636)h。两组比较差异显著(P<005)。结论适当的过度通气治疗脑疝可明显提高抢救成功率,降低病死率与病残率。
Objective To observe the curative effect of controlled hyperventilation on children with cerebral hernia. Methods 10 cases of children with cerebral hernia were treated with controlled hyperventilation at the same time and compared with 23 cases of normal hernia. Results The control group died of 21 cases, two cases of successful rescue. In addition to treatment group 3 patients gave up treatment and died, all rescue success. The difference between the two groups was significant (P <001). The average time for cohort score ≥8 in treatment-successful patients during treatment was (1614 ± 1036) h and that in control group was (335 ± 636) h. The difference between the two groups was significant (P <005). Conclusion Appropriate hyperventilation treatment of hernia can significantly improve the success rate of rescue and reduce mortality and morbidity.