遗传性肾炎,从广义上讲系指一组与遗传有关系的肾小球肾炎。其中Alport氏综合征最常见,因此狭义的遗传性肾炎即指Alport氏综合征而言。自1927年Alport氏作了一个家系肾炎同时伴有神经性耳聋的家系报告后引起人们普遍重视。本病虽不多见,但若能充分认识。也并非罕见。我们自1982年4月——1983年3月共收住5例亦即5个家系遗传性肾炎,现报道如下。病例1:男、20岁,汉族,待业青年,1岁半发生血尿,“感冒”时加重,9岁听力减退伴耳鸣,19岁出现视力模糊,自幼反应迟钝、记忆差。三兄均在1岁半发生血尿,相继出现耳聋视力障碍(均为白内障),母亲、妹妹、舅舅、外祖母、舅祖均 Hereditary nephritis, broadly speaking, refers to a group of genetically related glomerulonephritis. Alport’s syndrome is the most common, so the narrow sense of hereditary nephritis refers to Alport’s syndrome. Since 1927 Alport has made a family history of nephritis accompanied by deafness of the family reported aroused widespread attention. Although the rare disease, but if fully aware. It is not uncommon. We since April 1982 - 1983 March received a total of 5 cases that 5 family hereditary nephritis, are reported below. Case 1: Male, 20 years old, Han nationality, unemployed youth, 1 year and a half with hematuria, “cold” increased, 9-year-old hearing loss with tinnitus, 19 years old, blurred vision, childhood unresponsive, poor memory. Three brothers were hematuria in 1 year and a half, have deafness visual impairment (all cataracts), mother, sister, uncle, grandmother, uncle