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百乐君或盐酸氯胍又称为白乐君或氯苯胍等,对瘧原虫尤其是恶性瘧的红细胞外期效果较好,故自1945年问世以来,都采用作为瘧疾的预防药物。但在应用过程中,主要是由于超量给药而引起的急性中毒,在国内外文献中时有报导。现就有关的几个主要问题综述如下:药理学百乐君系白色、无臭、微苦的小结晶体,稍溶于水及酒精。现用制剂均系口服(另有醋酸盐可供静脉注射,但易刺激静脉发炎),口
Prunella or guanidine hydrochloride, also known as bailujun or chlorpromazine, on the extra-erythrocytic stage of Plasmodium, especially Plasmodium falciparum, the effect is good, so since its inception in 1945, are used as a preventive drug against malaria. However, in the process of application, acute poisoning caused mainly by overdosage has been reported in the domestic and foreign literatures. Now on the several major issues are summarized as follows: Pharmacology Baile Jun Department of white, odorless, slightly bitter crystals, slightly soluble in water and alcohol. The active agents are oral (another acetate for intravenous injection, but easy to stimulate vein inflammation), mouth