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Objective:To assess the 10-year incidence of retinal vein occlusion(RVO)and its predictors in an older population.Methods:The Blue Mountains Eye Study examined 3654 residents aged 49 years and older(82.4% response)from 1992 to 1994,reexamined 2335 residents(75.1% of survivors)from 1997 to 1999,and reexamined 1952 residents(75.6% of survivors)from 2002 to 2004.Incident RVO was assessed from stereoscopic retinal photographs.Kaplan-Meier cumulative 10-year incidence was calculated.Results:After excluding 47 residents with RVO at baseline and 171 residents with no photographs at either followup examination,2346 residents were considered at risk of developing RVO.The cumulative 10-year incidence of RVO was 1.6%.Age was significantly associated with the incidence of RVO(P=.03,Mantel-Haenszel χ 2 test for trend).Factors predicting the incidence of RVO included mean arterial blood pressure(age-adjusted odds ratio OR,1.41 per 10-mm Hg increase),ocular perfusion pressure(OR,1.71 per 10-mm Hg increase),obesity(OR,2.16),and presence of retinal arteriolar wall signs(focal narrowing:OR,3.37;arteriovenous nicking:OR,4.09;and opacification:OR,4.89).Conclusions:Older age(≥ 70 years),increasing mean arterial blood pressure,and atherosclerotic retinal vessel signs were significant predictors of incident RVO.
Objective: To assess the 10-year incidence of retinal vein occlusion (RVO) and its predictors in an older population. Methods: The Blue Mountains Eye Study examined 3654 people aged 49 years and older (82.4% response) from 1992 to 1994, reexamined 2335 residents (75.1% of survivors) from 1997 to 1999, and reexamined 1952 residents (75.6% of survivors) from 2002 to 2004. Incident RVO was assessed from stereoscopic retinal photographs. Kaplan-Meier cumulative 10-year incidence was calculated. Results: After excluding 47 residents with RVO at baseline and 171 residents with no photographs at either followup examination, 2346 residents were considered at risk of developing RVO. The cumulative 10-year incidence of RVO was 1.6%. Age was significantly associated with the incidence of RVO (P = .03, Mantel-Haenszel χ 2 test for trend) .Factors predicting the incidence of RVO included mean arterial blood pressure (age-adjusted odds ratio OR, 1.41 per 10-mm Hg increase), ocular perfusion pressure (OR, 1.71 per 10-mm Hg in crease, obesity (OR, 2.16), and presence of retinal arteriolar wall signs (focal narrowing: OR, 3.37; arteriovenous nicking: OR, 4.09; and opacification: OR, increasing mean arterial blood pressure, and atherosclerotic retinal vessel signs were significant predictors of incident RVO.