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按随机原则对上海市不同地区共２５００名成年人，用当面填写问卷方式进行胃食管反流相关症状及其影响因素的流行病学调查。将烧心、反酸及反食作为提示胃食管反流病的主要症状，并根据上述三种症状轻重进行症状记分。记分≥６分为病例组，≤５分为对照组。结果发现，上海地区胃食管反流相关症状发生率为７．６８％，男女间发生率无明显差异，但不同年龄、不同职业症状发生率相差显著（Ｐ＜０．０５）。病例组中呃逆、咳嗽、喘息等症状发生率及口腔溃疡、咽喉炎、肺炎、糖尿病等疾病的发生率均高于对照组（Ｐ＜０．０５），且常有进食过饱、饮用酸性饮料等生活习惯，并常患便秘（Ｐ＜０．０５）。提示上海地区胃食管反流相关症状并非少见，且症状发生与多种因素有关。
According to the principle of randomness, a total of 2,500 adults in different areas of Shanghai were surveyed by face-to-face questionnaire to investigate the epidemiological characteristics of gastroesophageal reflux related symptoms and its influencing factors. Will be heartburn, acid reflux and anti-food as a reminder of gastroesophageal reflux disease of the main symptoms, and symptoms according to the severity of the above three symptoms score. Scores ≥6 were divided into cases, ≤5 points for the control group. The incidence of gastroesophageal reflux-related symptoms in Shanghai was 7.68%. There was no significant difference between male and female rates, but the incidence rates of different occupational symptoms were significantly different (P <0.05). The incidence of symptoms such as hiccups, coughing and wheezing and the incidence of oral ulcer, sore throat, pneumonia and diabetes in case group were higher than those in control group (P <0.05) And other habits, and often constipation (P <0.05). Tip Shanghai gastroesophageal reflux related symptoms are not uncommon, and the occurrence of symptoms and a variety of factors.