目的观察兔慢性细菌性前列腺炎(CBP)的尿流动力学变化。方法选用健康雄性大白兔,依文献方法,通过后尿道反复灌注大肠埃希菌制备CBP动物模型:模型成功后进行尿流动力学测定。结果与正常组相比,模型组主要表现为最大逼尿肌压、最大尿道压明显升高,而膀胱容量及顺应性无明显改变。结论兔慢性细菌性前列腺炎尿流动力学指标具有一定程度的异常改变,并可能与其发病机制密切相关。 Objective To observe the changes of urodynamics in chronic bacterial prostatitis (CBP) in rabbits. Methods Healthy male rabbits were selected and CBP animal model was established by repeated perfusion of Escherichia coli through the posterior urethra according to the literature method. Urodynamic study was performed after successful model. Results Compared with the normal group, the model group showed the maximal detrusor pressure, the maximal urethral pressure increased significantly, while the bladder capacity and compliance did not change significantly. Conclusion The urodynamic indexes of chronic bacterial prostatitis in rabbits have a certain degree of abnormal changes and may be closely related to its pathogenesis.