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目的:探究甲巯咪唑联合普萘洛尔治疗甲状腺功能亢进患者的临床疗效。方法:回顾性分析本院2009年12月至2013年12月收治的132例甲状腺功能亢进患者临床资料,所有患者随机分成两组,联合用药组采用甲巯咪唑联合普萘洛尔进行治疗,对照组仅采用甲巯咪唑进行治疗,比较两组的治疗效果。结果:治疗3个月后,联合用药组患者的疗效、总甲状腺素、游离甲状腺素、总三碘甲状腺原氨酸、游离三碘甲状腺原氨酸和高敏促甲状腺素水平与对照组患者相比改善效果更加显著,差异具有统计学意义(P<0.05)。结论:临床上采用甲巯咪唑联合普萘洛尔治疗甲状腺功能亢进的疗效更加确切,安全性能高,值得临床推广使用。
Objective: To investigate the clinical efficacy of methimazole combined with propranolol in patients with hyperthyroidism. Methods: The clinical data of 132 patients with hyperthyroidism admitted from December 2009 to December 2013 in our hospital were retrospectively analyzed. All patients were randomly divided into two groups. The combination group was treated with methimazole combined with propranolol, and the control group Group only with methimazole treatment, the treatment effect of the two groups were compared. RESULTS: After 3 months of treatment, the efficacy, total thyroxine, free thyroxine, total triiodothyronine, free triiodothyronine and hypersensitivity thyroxine in the combination group were significantly higher than those in the control group The improvement effect was more significant, the difference was statistically significant (P <0.05). Conclusion: The clinical efficacy of methimazole combined with propranolol for the treatment of hyperthyroidism is more exact and safe, which is worthy of clinical promotion.