论文部分内容阅读
目的探讨成人麻疹患者出疹期、恢复期T淋巴细胞表达水平的变化。方法应用流式细胞术分别测定出疹期、恢复期和健康对照者外周血CD+3、CD+4、CD+8T淋巴细胞数目。结果成人麻疹患者出疹期外周血CD+3、CD+4T淋巴细胞数目较健康对照者明显下降(P<0.05),恢复期CD+3、CD+4T淋巴细胞数目上升(P<0.05)。结论检测成人麻疹患者外周血T淋巴细胞数目变化,有助于了解机体的免疫状况,对临床诊治具有重要参考价值。
Objective To investigate the changes of T lymphocyte expression level during the period of rash and convalescence in adult measles patients. Methods The number of CD + 3, CD + 4, CD + 8T lymphocytes in peripheral blood of the rash, convalescent and healthy controls were determined by flow cytometry. Results The number of CD + 3 and CD + 4T lymphocytes in peripheral blood of adult measles patients was significantly lower than that of healthy controls (P <0.05). The numbers of CD + 3 and CD + 4T lymphocytes in convalescent stage were increased (P <0.05). Conclusion The detection of changes in the number of T lymphocytes in peripheral blood of adult measles patients helps to understand the immune status of the patients and has important reference value for clinical diagnosis and treatment.