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目的调查我院近3年围手术期抗菌药物使用情况,了解使用中存在的主要问题,为促进临床合理应用提供依据。方法采用回顾性调查的方法,从我院病案室2005年1月-2007年12月间11631份手术病历中,每手术科室每月随机抽取2份,共计432份病历,对抗菌药物应用情况进行调查。结果432份病历中,抗菌药物的使用率为100%,其中抗菌药物应用合理的病历比例平均为1.85%,基本合格的为18.98%,不合格的为79.17%,3年合格率无明显差异,应用不合理病历中,预防性应用抗菌药物用药时机不合理的比例平均为100%;治疗性应用抗菌药物不合理比例平均为96%,用法用量不正确及药物选择不正确的比例平均为60%和37%。结论我院围手术期抗菌药物不合理使用情况比较严重,应在继续加强医师合理用药培训的基础上,制定具体的抗菌药物临床应用监管措施,充分发挥药师作用,提高抗菌药物应用水平。
Objective To investigate the use of perioperative antibiotics during the past three years in our hospital to understand the main problems in use and provide the basis for the promotion of clinical rational use. Methods A retrospective survey method was used to analyze the clinical data of 11631 surgical records from January 2005 to December 2007 in our hospital from January 2005 to December 2007, and each surgical department randomly selected 2 copies per month for a total of 432 medical records, survey. Results Among the 432 medical records, the use rate of antibacterials was 100%. Among them, the average medical records of antibacterials were 1.85%, 18.98% and 79.17%, respectively. There was no significant difference in the 3-year pass rates, The application of unreasonable medical records, prophylactic use of antimicrobial drugs irrational timing of an average of 100%; therapeutic use of antimicrobial drugs irrational proportion of an average of 96%, usage dosage is incorrect and the proportion of drug selection is not an average of 60% And 37%. Conclusions In our hospital, the unreasonable use of antimicrobial agents is rather serious. On the basis of continuing to strengthen the training of physicians on rational drug use, we should formulate specific clinical supervision measures for antimicrobial agents, give full play to the role of pharmacists and improve the application of antimicrobial agents.