患者男,43岁。面部多发性“色素痣”10年。皮肤科情况:前额、面中央及双上肢各见数枚芝麻至米粒大小黑褐色丘疹,部分表面凹凸不平,色素不均,界限不甚清晰。双手掌可见密集针尖大小点状凹陷。皮损组织病理示:真皮内可见大小形状不一的肿瘤团块,瘤体细胞由基底样细胞构成,肿瘤周围细胞呈栅栏状排列,肿瘤内见大量色素颗粒,并可见收缩间隙。诊断:痣样基底细胞癌综合征。 Male patient, 43 years old. Multiple facial “pigmented nevus” 10 years. Dermatology: the forehead, the surface of the central and upper extremities each see several sesame seeds to the size of dark brown papules, some uneven surface, uneven pigment, the boundaries are not clear. Visible double-pointed tip of the size of the point-like depression. Histopathological examination showed that the size, shape and size of the tumor mass were visible in the dermis. The tumor cells were composed of basal-like cells. The cells around the tumor were arranged in a palisade pattern. A large number of pigment granules were seen in the tumor and shrinkage space was observed. Diagnosis: nevus-like basal cell carcinoma syndrome.